Several children in Madhya Pradesh and Rajasthan died after being given a cough syrup called “Coldrif”, made by Sresan Pharmaceuticals, a company located in Kanchipuram, Tamil Nadu, India.
At least 9 to 11 children have died after drinking a cough syrup that may have been contaminated with poisonous chemicals.
The investigation has started to find out what happened. Before children died, Doctor noticed the symptoms like vomiting, very little urine, and breathing problems. Many others children are admited in the hospitals.
The samples of that syrup have been sent for testing. After testing they conformed that it contain diethylene glycol (DEG) which is a harmful chemical that can damage the kidneys and lead to death. The amount of DEG found is 48.6% in one batch that's more than safety limit.
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In recent times, similar incident has occurred in many countries like Gambia and Uzbekistan. The police has arrested a Dr. Praveen Soni, who prescribed the syrup. The central drug regulator (CDSCO) is inspecting many other manufacturing companies.
Pediatrician suggest that over the counter cough medicines should not be given to children under two years of age.
What is DEG and EG?
DEG is Diethylene Glycol which is colourless, sweet in taste and thick liquid. It is not safe for medicine or food.
- It is used to make paints, varnishes, and resins.
- It is also used as a solvent in printing inks and dyes.
- Many company also used in cosmetic products and toothpaste.
- Plastic industry used in plastic and polyester fiber production.
- This chemical is used in antifreeze and brake fluids.
EG is Ethylene Glycol which is colorless and sweet in taste. After consuming this chemicals it change into toxic acid which damage kidney and central nervous system.
- It is the main ingredient in antifreeze and coolants for cars.
- It is used in air conditioning and refrigeration systems.
What is the safety limit of DEG and EG?
According to World Health Organisation (WHO):-
Not more than 0.10% V/V of DEG and EG in any pharmaceuticals products.
If the small amount is above than limit it can cause liver damage, kidney failure in children.
Why Pharmaceuticals companies are still using DEG or EG in medicine preparation?
DEG and EG is used in syrup to make syrup sweet and smooth in nature. The small pharmaceuticals company are using DEG and EG to save money which play vital role in children death. It is cheaper than glycerin and propylene glycol in price. So pharmaceuticals company should use glycerin and propylene glycol to make cough syrup smooth and sweety taste which is safe for medicine and food.
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